Describe the SACT regimen in detail, what drugs are involved, how do these drugs work towards killing cancer, drawing on the underpinning literature.
Chemotherapy drugs used in SACT are typically categorized based on their mechanism of action. Some drugs directly attack cancer cells by interfering with their ability to divide and grow, while others target the blood vessels that supply the cancer cells with nutrients, oxygen, and other necessary materials.
One common SACT regimen is the combination of cyclophosphamide, doxorubicin, and vincristine (CAV), also known as the CHOP regimen. This regimen is used to treat non-Hodgkin’s lymphoma and other types of ca
Looking for a similar assignment?
Let Us write for you! We offer custom paper writing services
Another commonly used SACT regimen is FOLFOX, which is used to treat colorectal cancer. This regimen includes the drugs oxaliplatin, leucovorin, and 5-fluorouracil (5-FU). Oxaliplatin is a platinum-based chemotherapy drug that works by binding to DNA and inhibiting cell division. Leucovorin is a form of folic acid that enhances the effectiveness of 5-FU, which is a chemotherapy drug that inhibits cell division and replication.
In addition to these drugs, other drugs such as bevacizumab and cetuximab may be added to the SACT regimen to target the blood vessels that supply cancer cells with nutrients, oxygen, and other necessary materials. These drugs are known as targeted therapies and work by inhibiting the formation of new blood vessels in tumors, which can slow or stop the growth of cancer cells.
While SACT can be an effective treatment for cancer, it can also cause side effects, including nausea, vomiting, hair loss, and fatigue. However, advances in cancer research and drug development have led to the development of newer chemotherapy drugs that are less toxic and have fewer side effects.
Overall, SACT is an important component of cancer treatment, and its success is based on the selection of the most appropriate drugs for the specific cancer being treated, as well as the overall health of the patient.